amfAR, The Foundation for AIDS Research

Publications from amfAR Grantees and Fellows

Click here for publications prior to 2013.

Publications of amfAR Grantees and Fellows


Each month, the findings of amfAR-funded researchers (names in bold) are published in peer-reviewed journals, which are listed below by month of publication. In each case you can click on the “ABSTRACT” link for a brief summary of the research paper as it appears in the journal. In some cases, you can click on the "READ MORE" link to access related articles written for a lay audience by amfAR staff. 

February 2017

Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection.
Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY.
JAMA Cardiol. 2017 Feb 1;2(2):163-171.
READ MORE: Aging with HIV: Concerns About Accelerated Heart Disease

Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.
Nguyen K, Das B, Dobrowolski C, Karn J.
MBio. 2017 Feb 28;8(1). pii: e00133-17.


January 2017

The interferon paradox: can inhibiting an antiviral mechanism advance an HIV cure?
Deeks SG, Odorizzi PM, Sekaly RP.
J Clin Invest. 2017 Jan 3;127(1):103-105.
READ MORE: Understanding the ‘Interferon Paradox:’ A Novel Approach to Eradicating HIV

A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse.
Bloch N, Gläsker S, Sitaram P, Hofmann H, Shepard CN, Schultz ML, Kim B, Landau NR.
J Biol Chem. 2017 Jan 20;292(3):1068-1080.

Cancer therapies in HIV cure research.
Rasmussen TA, Anderson JL, Wightman F, Lewin SR.
Curr Opin HIV AIDS. 2017 Jan;12(1):96-104.


December 2016

Porphyromonas gingivalis-mediated signaling through TLR4 mediates persistent HIV infection of primary macrophages.
Agosto LM, Hirnet JB, Michaels DH, Shaik-Dasthagirisaheb YB, Gibson FC, Viglianti G, Henderson AJ.
Virology. 2016 Dec;499:72-81.

TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes.
Hofmann H, Vanwalscappel B, Bloch N, Landau NR.
Retrovirology. 2016 Dec 1;13(1):83.

Engineering HIV-Specific Immunity with Chimeric Antigen Receptors.
Kitchen SG, Zack JA.
AIDS Patient Care STDS. 2016 Dec;30(12):556-561.

Euphorbia Kansui Reactivates Latent HIV.
Cary DC, Fujinaga K, Peterlin BM.
PLoS One. 2016 Dec 15;11(12):e0168027

The mTOR Complex Controls HIV Latency.
Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E.
Cell Host Microbe. 2016 Dec 14;20(6):785-797.

November 2016

Lineage-Specific Differences between the gp120 Inner Domain Layer 3 of Human Immunodeficiency Virus and That of Simian Immunodeficiency Virus.
Ding S, Medjahed H, Prévost J, Coutu M, Xiang SH, Finzi A.
J Virol. 2016;90(22):10065-10073.


Monitoring Integration over Time Supports a Role for Cytotoxic T Lymphocytes and Ongoing Replication as Determinants of Reservoir Size.
Pinzone MR, Graf E, Lynch L, McLaughlin B, Hecht FM, Connors M, Migueles SA, Hwang WT, Nunnari G, O'Doherty U.
J Virol. 2016;90(23):10436-10445.
READ MORE: Following HIV Reservoirs: Impact of ART and Its Timing


Quantitative evaluation of the antiretroviral efficacy of dolutegravir.
Laskey SB, Siliciano RF.
JCI Insight. 2016;1(19):e90033.

October 2016

Ongoing Clinical Trials of Human Immunodeficiency Virus Latency-Reversing and Immunomodulatory Agents.
Delagrèverie HM, Delaugerre C, Lewin SR, Deeks SG, Li JZ.
Open Forum Infect Dis. 2016 Oct 7;3(4):ofw189.


Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.
Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, Martin L, Tremblay C, Hahn BH, Kaufmann DE, Wu X, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A.
EBioMedicine. 2016 Oct;12:208-218.


Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins.
Herschhorn A, Ma X, Gu C, Ventura JD, Castillo-Menendez L, Melillo B, Terry DS, Smith AB 3rd, Blanchard SC, Munro JB, Mothes W, Finzi A, Sodroski J.
MBio. 2016 Oct 25;7(5). pii: e01598-16.


Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR.
Mavigner M, Lee ST, Habib J, Robinson C, Silvestri G, O'Doherty U, Chahroudi A.
J Virus Erad. 2016 Oct 5;2(4):219-226.


Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay.
Trypsteen W, Mohammadi P, Van Hecke C, Mestdagh P, Lefever S, Saeys Y, De Bleser P, Vandesompele J, Ciuffi A, Vandekerckhove L, De Spiegelaere W.
Sci Rep. 2016 Oct 26;6:36111.


CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles.
Leong YA, Chen Y, Ong HS, Wu D, Man K, Deleage C, Minnich M, Meckiff BJ, Wei Y, Hou Z, Zotos D, Fenix KA, Atnerkar A, Preston S, Chipman JG, Beilman GJ, Allison CC, Sun L, Wang P, Xu J, Toe JG, Lu HK, Tao Y, Palendira U, Dent AL, Landay AL, Pellegrini M, Comerford I, McColl SR, Schacker TW, Long HM, Estes JD, Busslinger M, Belz GT, Lewin SR, Kallies A, Yu D.
Nat Immunol. 2016 Oct;17(10):1187-96.

September 2016

Porphyromonas gingivalis-mediated signaling through TLR4 mediates persistent HIV infection of primary macrophages.
Agosto LM, Hirnet JB, Michaels DH, Shaik-Dasthagirisaheb YB, Gibson FC, Viglianti G, Henderson AJ.
Virology. 2016 Sep 15;499:72-81.

Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals.
Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Charlebois R, Massanella M, Brassard N, Alsahafi N, Delgado GG, Routy JP, Walker BD, Finzi A, Chomont N, Kaufmann DE.
Cell Host Microbe. 2016 Sep 14;20(3):368-80.

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.
Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, Martin L, Tremblay C, Hahn BH, Kaufmann DE, Wu X, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A.
EBioMedicine. 2016 Sep 9. pii: S2352-3964(16)30412-1. 

Standard vaccines increase HIV-1 transcription during antiretroviral therapy.
Yek C, Gianella S, Plana M, Castro P, Scheffler K, García F, Massanella M, Smith DM.
AIDS. 2016 Sep 24;30(15):2289-98.

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes.
Pérez-Santiago J, Ouchi D, Urrea V, Carrillo J, Cabrera C, Villà-Freixa J, Puig J, Paredes R, Negredo E, Clotet B, Massanella M, Blanco J.
AIDS. 2016 Sep 24;30(15):2275-87.
READ MORE:  More Than One Way to Activate a Virus

Broad activation of latent HIV-1 in vivo.
Barton K, Hiener B, Winckelmann A, Rasmussen TA, Shao W, Byth K, Lanfear R, Solomon A, McMahon J, Harrington S, Buzon M, Lichterfeld M, Denton PW, Olesen R, Østergaard L, Tolstrup M, Lewin SR, Søgaard OS, Palmer S.
Nat Commun. 2016 Sep 8;7:12731.
READ MORE:  More Than One Way to Activate a Virus

Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells.
Hansen EC, Ransom M, Hesselberth JR, Hosmane NN, Capoferri AA, Bruner KM, Pollack RA, Zhang H, Drummond MB, Siliciano JM, Siliciano R, Stivers JT.
Elife. 2016 Sep 20;5. pii: e18447.

Defective proviruses rapidly accumulate during acute HIV-1 infection.
Bruner KM, Murray AJ, Pollack RA, Soliman MG, Laskey SB, Capoferri AA, Lai J, Strain MC, Lada SM, Hoh R, Ho YC, Richman DD, Deeks SG, Siliciano JD, Siliciano RF.
Nat Med. 2016 Sep;22(9):1043-9.

August 2016

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy.
Lee SA, Bacchetti P, Chomont N, Fromentin R, Lewin SR, O'Doherty U, Palmer S, Richman DD, Siliciano JD, Yukl SA, Deeks SG, Burbelo PD.
PLoS One. 2016 Aug 2;11(8):e0160192.

Advances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring.
Lifson MA, Ozen MO, Inci F, Wang S, Inan H, Baday M, Henrich TJ, Demirci U.
Adv Drug Deliv Rev. 2016 Aug 1;103:90-104.

Identification of Siglec-1 null individuals infected with HIV-1.
Martinez-Picado J, McLaren PJ, Erkizia I, Martin MP, Benet S, Rotger M, Dalmau J, Ouchi D, Wolinsky SM, Penugonda S, Günthard HF, Fellay J, Carrington M, Izquierdo-Useros N, Telenti A.
Nat Commun. 2016 Aug 11;7:12412.

T-cell therapies for HIV: Preclinical successes and current clinical strategies.
Patel S, Jones RB, Nixon DF, Bollard CM.
Cytotherapy. 2016 Aug;18(8):931-42.

Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality.
Laskey SB, Pohlmeyer CW, Bruner KM, Siliciano RF.
PLoS Pathog. 2016 Aug 5;12(8):e1005689.

In Vivo Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models.
Nakaya Y, Stavrou S, Blouch K, Tattersall P, Ross SR.
J Virol. 2016 Aug 12;90(17):8005-12.

July 2016

HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-κB.
Saleh S, Lu HK, Evans V, Harisson D, Zhou J, Jaworowski A, Sallmann G, Cheong KY, Mota TM, Tennakoon S, Angelovich TA, Anderson J, Harman A, Cunningham A, Gray L, Churchill M, Mak J, Drummer H, Vatakis DN, Lewin SR, Cameron PU.
Retrovirology. 2016 Jul 26;13(1):49.

Initiation of Antiretroviral Therapy Restores CD4+ T Memory Stem Cell Homeostasis in Simian Immunodeficiency Virus-Infected Macaques.
Cartwright EK, Palesch D, Mavigner M, Paiardini M, Chahroudi A, Silvestri G.
J Virol. 2016 Jul 11;90(15):6699-708.

Animal models to achieve an HIV cure.
Kumar N, Chahroudi A, Silvestri G.
Curr Opin HIV AIDS. 2016 Jul;11(4):432-41.

Strategies for targeting residual HIV infection.
Chomont N, Perreau M.
Curr Opin HIV AIDS. 2016 Jul;11(4):359-61.

Persistent HIV-1 replication during antiretroviral therapy.
Martinez-Picado J, Deeks SG.
Curr Opin HIV AIDS. 2016 Jul;11(4):417-23.

CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.
Fromentin R, Bakeman W, Lawani MB, Khoury G, Hartogensis W, DaFonseca S, Killian M, Epling L, Hoh R, Sinclair E, Hecht FM, Bacchetti P, Deeks SG, Lewin SR, Sékaly RP, Chomont N.
PLoS Pathog. 2016 Jul 14;12(7):e1005761.

Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation.
Li P, Kaiser P, Lampiris HW, Kim P, Yukl SA, Havlir DV, Greene WC, Wong JK.
Nat Med. 2016 Jul;22(7):807-11.

Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model.
Zhen A, Rezek V, Youn C, Rick J, Lam B, Chang N, Zack J, Kamata M, Kitchen S.
J Vis Exp. 2016 Jul 2;(113).

Shocking HIV out of hiding: where are we with clinical trials of latency reversing agents?
Rasmussen TA, Lewin SR.
Curr Opin HIV AIDS. 2016 Jul;11(4):394-401.

Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-α Resistance.
Boyd DF, Sharma A, Humes D, Cheng-Mayer C, Overbaugh J.
PLoS Pathog. 2016 Jul 11;12(7):e1005727

The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence.
Murray AJ, Kwon KJ, Farber DL, Siliciano RF.
J Immunol. 2016 Jul 15;197(2):407-17.

June 2016

Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency.
Bournazos S, Gazumyan A, Seaman MS, Nussenzweig MC, Ravetch JV.
Cell. 2016 Jun 16;165(7):1609-20.

Brief Report: Effect of CMV and HIV Transcription on CD57 and PD-1 T-Cell Expression During Suppressive ART.
Dan JM, Massanella M, Smith DM, Spina CA, Schrier R, Daar ES, Dube MP, Morris SR, Gianella S.
J Acquir Immune Defic Syndr. 2016 Jun 1;72(2):133-7.

Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis.
Li Q, Karim AF, Ding X, Das B, Dobrowolski C, Gibson RM, Quiñones-Mateu ME, Karn J, Rojas RE.
Sci Rep. 2016 Jun 14;6:27566.

Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.
Kong L, He L, de Val N, Vora N, Morris CD, Azadnia P, Sok D, Zhou B, Burton DR, Ward AB, Wilson IA, Zhu J.
Nat Commun. 2016 Jun 28;7:12040.

Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.
Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK.
PLoS Pathog. 2016 Jun 2;12(6):e1005677.

Immunologic profiles distinguish aviremic HIV-infected adults.
Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW.
AIDS. 2016 Jun 19;30(10):1553-62.

The effect of HIV-1 Vif polymorphisms on A3G anti-viral activity in an in vivo mouse model.
Cadena C, Stavrou S, Manzoni T, Iyer SS, Bibollet-Ruche F, Zhang W, Hahn BH, Browne EP, Ross SR.
Retrovirology. 2016 Jun 30;13(1):45.

May 2016

Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo.
Lu CL, Murakowski DK, Bournazos S, Schoofs T, Sarkar D, Halper-Stromberg A, Horwitz JA, Nogueira L, Golijanin J, Gazumyan A, Ravetch JV, Caskey M, Chakraborty AK, Nussenzweig MC.
Science. 2016 May 20;352(6288):1001-4

HIV-1 Reservoirs During Suppressive Therapy.
Barton K, Winckelmann A, Palmer S.
Trends Microbiol. 2016 May;24(5):345-55.

Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.
Tully DC, Ogilvie CB, Batorsky RE, Bean DJ, Power KA, Ghebremichael M, Bedard HE, Gladden AD, Seese AM, Amero MA, Lane K, McGrath G, Bazner SB, Tinsley J, Lennon NJ, Henn MR, Brumme ZL, Norris PJ, Rosenberg ES, Mayer KH, Jessen H, Kosakovsky Pond SL, Walker BD, Altfeld M, Carlson JM, Allen TM.
PLoS Pathog. 2016 May 10;12(5):e1005619.


April 2016

Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques.
Hessell AJ, Jaworski JP, Epson E, Matsuda K, Pandey S, Kahl C, Reed J, Sutton WF, Hammond KB, Cheever TA, Barnette PT, Legasse AW, Planer S, Stanton JJ, Pegu A, Chen X, Wang K, Siess D, Burke D, Park BS, Axthelm MK, Lewis A, Hirsch VM, Graham BS, Mascola JR, Sacha JB, Haigwood NL.
Nat Med. 2016 Apr;22(4):362-8.

A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.
Jones RB, Mueller S, O'Connor R, Rimpel K, Sloan DD, Karel D, Wong HC, Jeng EK, Thomas AS, Whitney JB, Lim SY, Kovacs C, Benko E, Karandish S, Huang SH, Buzon MJ, Lichterfeld M, Irrinki A, Murry JP, Tsai A, Yu H, Geleziunas R, Trocha A, Ostrowski MA, Irvine DJ, Walker BD.
PLoS Pathog. 2016 Apr 15;12(4):e1005545.

Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Chen Y, Deller MC, Hao Y, Feng Y, Garces F, Wilson R, Dai K, O'Dell S, McKee K, Mascola JR, Ward AB, Wyatt RT, Li Y, Wilson IA, Zhu J, Shao Y.
Immunity. 2016 Apr 19;44(4):939-50.

How to Define the Latent Reservoir: Tools of the Trade.
Barton KM, Palmer SE.
Curr HIV/AIDS Rep. 2016 Apr;13(2):77-84.

Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.
Hill AL, Rosenbloom D, Goldstein E3 Hanhauser E, Kuritzkes DR, Siliciano RF, Henrich TJ.
PLoS Pathog. 2016 Apr 27;12(4):e1005535.


March 2016

Residual inflammation and viral reservoirs: alliance against an HIV cure.
Massanella M, Fromentin R, Chomont N.
Curr Opin HIV AIDS. 2016 Mar;11(2):234-41.
READ MORE: Breaking a Vicious Circle - Controlling HIV Reservoirs by Targeting Inflammation

CCR5-Δ32 Heterozygosity, HIV-1 Reservoir Size, and Lymphocyte Activation in Individuals Receiving Long-term Suppressive Antiretroviral Therapy.
Henrich TJ, Hanhauser E, Harrison LJ, Palmer CD, Romero-Tejeda M, Jost S, Bosch RJ, Kuritzkes DR.
J Infect Dis. 2016 Mar 1;213(5):766-70.

Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection.
Gianella S, Anderson CM, Var SR, Oliveira MF, Lada SM, Vargas MV, Massanella M, Little SJ, Richman DD, Strain MC, Pérez-Santiago J, Smith DM.
J Virol. 2016 Mar 28;90(8):3944-52.

Macrophages and HIV-1: An Unhealthy Constellation.
Sattentau QJ, Stevenson M.
Cell Host Microbe. 2016 Mar 9;19(3):304-10.


February 2016

Adenosine deaminase regulates Treg expression in autologous T cell-dendritic cell cocultures from patients infected with HIV-1.
Naval-Macabuhay I, Casanova V, Navarro G, García F, León A, Miralles L, Rovira C, Martinez-Navio JM, Gallart T, Mallol J, Gatell JM, Lluís C, Franco R, McCormick PJ, Climent N.
J Leukoc Biol. 2016 Feb;99(2):349-59.

HIV-specific CD8+ T cells and HIV eradication.
Jones RB, Walker BD.
J Clin Invest. 2016 Feb 1;126(2):455-63.

Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques.
Ryan ES, Micci L, Fromentin R, Paganini S, McGary CS, Easley K, Chomont N, Paiardini M.
PLoS Pathog. 2016 Feb 1;12(2):e1005412.
READ MORE: Attacking HIV in the Gut

SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage.
Evans TI, Li H, Schafer JL, Klatt NR, Hao XP, Traslavina RP, Estes JD, Brenchley JM, Reeves RK.
J Infect Dis. 2016 Feb 1;213(3):361-9.

Recent developments in the effort to cure HIV infection: going beyond N = 1.
Siliciano JD, Siliciano RF.
J Clin Invest. 2016 Feb 1;126(2):409-14.


January 2016

Ethics of ART interruption after stem-cell transplantation.
Sugarman J, Lewin SR, Henrich TJ, Rasmussen TA.
Lancet HIV. 2016 Jan;3(1):e8-e10.
READ MORE: The Science, and Ethics, of Stopping ART in Assessing Possible HIV Cures

Analysis of HIV-1 Gag-RNA Interactions in Cells and Virions by CLIP-seq.
Kutluay SB, Bieniasz PD.
Methods Mol Biol. 2016;1354:119-31

Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure.
Martin AR, Siliciano RF.
Annu Rev Med. 2016 Jan 14;67:215-28

December 2015

Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.
Cubas R, van Grevenynghe J, Wills S, Kardava L, Santich BH, Buckner CM, Muir R, Tardif V, Nichols C, Procopio F, He Z, Metcalf T, Ghneim K, Locci M, Ancuta P, Routy JP, Trautmann L, Li Y, McDermott AB, Koup RA, Petrovas C, Migueles SA, Connors M, Tomaras GD, Moir S, Crotty S, Haddad EK.
J Immunol. 2015 Dec 15;195(12):5625-36.

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study.
Elliott JH, McMahon JH, Chang CC, Lee SA, Hartogensis W, Bumpus N, Savic R, Roney J, Hoh R, Solomon A, Piatak M, Gorelick RJ, Lifson J, Bacchetti P, Deeks SG, Lewin SR.
Lancet HIV. 2015 Dec;2(12):e520-9.

Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1.
Rosenbloom DI, Elliott O, Hill AL, Henrich TJ, Siliciano JM, Siliciano RF. 
Open Forum Infect Dis. 2015 Aug 26;2(4):ofv123.

Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques.
Micci L, Ryan ES, Fromentin R, Bosinger SE, Harper JL, He T, Paganini S, Easley KA, Chahroudi A, Benne C, Gumber S, McGary CS, Rogers KA, Deleage C, Lucero C, Byrareddy SN, Apetrei C, Estes JD, Lifson JD, Piatak M Jr, Chomont N, Villinger F, Silvestri G, Brenchley JM, Paiardini M.
J Clin Invest. 2015 Dec 1;125(12):4497-513. 
READ MORE: Reducing Viral Reservoirs with Immune-Based Therapy

Mother-to-Child HIV-1 Transmission Events Are Differentially Impacted by Breast Milk and Its Components from HIV-1-Infected Women.
Shen R, Achenbach J, Shen Y, Palaia J, Rahkola JT, Nick HJ, Smythies LE, McConnell M, Fowler MG, Smith PD, Janoff EN.
PLoS One. 2015 Dec 17;10(12):e0145150.


November 2015

Lack of Evidence for Molecular Mimicry in HIV-Infected Subjects.
Burbelo PD, Klimavicz JS, Deeks SG, Kovacs JA, Ragheb JA.
PLoS One. 2015 Nov 23;10(11):e0127662.

Multiplexed highly-accurate DNA sequencing of closely-related HIV-1 variants using continuous long reads from single molecule, real-time sequencing.
Dilernia DA, Chien JT, Monaco DC, Brown MP, Ende Z, Deymier MJ, Yue L, Paxinos EE, Allen S, Tirado-Ramos A, Hunter E.
Nucleic Acids Res. 2015 Nov 16;43(20):e129

CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing.
Pak V, Eifler TT, Jäger S, Krogan NJ, Fujinaga K, Peterlin BM.
Cell Host Microbe. 2015 Nov 11;18(5):560-70.

Central memory CD4+ T cells are preferential targets of double infection by HIV-1.
Haqqani AA, Marek SL, Kumar J, Davenport M, Wang H, Tilton JC.
Virol J. 2015 Nov 11;12(1):184.

Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity.
Wahl A, Baker C, Spagnuolo RA, Stamper LW, Fouda GG, Permar SR, Hinde K, Kuhn L, Bode L, Aldrovandi GM, Garcia JV.
J Virol. 2015 Nov 1;89(21):10868-78.
READ MORE: Breast Milk Yields Clues to Natural Inhibitors of HIV


October 2015

Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.
Olesen R, Vigano S, Rasmussen TA, Søgaard OS, Ouyang Z, Buzon M, Bashirova A, Carrington M, Palmer S, Brinkmann CR, Yu XG, Østergaard L, Tolstrup M, Lichterfeld M. J Virol. 2015 Oct 15;89(20):10176-89 
READ MORE: A Prominent Role for Innate Immunity in Eradicating HIV

Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and rectal reservoirs.
Malatinkova E, De Spiegelaere W, Bonczkowski P, Kiselinova M, Vervisch K, Trypsteen W, Johnson M, Verhofstede C, de Looze D, Murray C, Kinloch-de Loes S, Vandekerckhove L. Elife. 2015 Oct 6;4. doi: 10.7554/eLife.09115.


September 2015

Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques.
Chowdhury A, Hayes TL, Bosinger SE, Lawson BO, Vanderford T, Schmitz JE, Paiardini M, Betts M, Chahroudi A, Estes JD, Silvestri G.
J Virol. 2015 Sep 1;89(17):8677-86.  
READ MORE: Taking Control of HIV

The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from Monkeys.
Etienne L, Bibollet-Ruche F, Sudmant PH, Wu LI, Hahn BH, Emerman M.
PLoS Pathog. 2015 Sep 22;11(9):e1005149.  

HIV-1 Reservoir Dynamics after Vaccination and Antiretroviral Therapy Interruption Are Associated with Dendritic Cell Vaccine-Induced T Cell Responses.
Andrés C, Plana M, Guardo AC, Alvarez-Fernández C, Climent N, Gallart T, León A, Clotet B, Autran B, Chomont N, Gatell JM, Sánchez-Palomino S, García F.
J Virol. 2015 Sep 15;89(18):9189-99.  

Comparison of digital PCR platforms and semi-nested qPCR as a tool to determine the size of the HIV reservoir.
Bosman KJ, Nijhuis M, van Ham PM, Wensing AM, Vervisch K, Vandekerckhove L, De Spiegelaere W.
Sci Rep. 2015 Sep 9;5:13811.  

Antigen-specific NK cell memory in rhesus macaques.
Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, von Andrian UH, Barouch DH.
Nat Immunol. 2015 Sep;16(9):927-32;
READ MORE: Natural Killers Adapt

Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR.
Sahu G, Farley K, El-Hage N, Aiamkitsumrit B, Fassnacht R, Kashanchi F, Ochem A, Simon GL, Karn J, Hauser KF, Tyagi M.
Virology. 2015 Sep;483:185-202.

Inhibition of HIV infection by caerin 1 antimicrobial peptides.
VanCompernolle S, Smith PB, Bowie JH, Tyler MJ, Unutmaz D, Rollins-Smith LA.
Peptides. 2015 Sep;71:296-303. doi: 10.1016/j.peptides.2015.05.004. Epub 2015 May 27.

August 2015

Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy.
von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, Boritz E, Deeks SG, Hecht FM, Palmer S.
J Infect Dis. 2015 Aug 15;212(4):596-607
READ MORE: Division or Multiplication: Exploring the Maintenance of the HIV Reservoir  

July 2015

The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency.
Mousseau G, Kessing CF, Fromentin R, Trautmann L, Chomont N, Valente ST.
MBio. 2015 Jul 7;6(4). pii: e00465-15.
READ MORE: Stabilize or Stimulate? A New Approach to Attacking the HIV Reservoir   

Robust regression methods for real-time polymerase chain reaction.
Trypsteen W, De Neve J, Bosman K, Nijhuis M, Thas O, Vandekerckhove L, De Spiegelaere W.
Anal Biochem. 2015 Jul 1;480:34-6. doi: 10.1016/j.ab.2015.04.001  

Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy.
Schafer JL, Li H, Evans TI, Estes JD, Reeves RK.
J Virol. 2015 Jul 1;89(13):6887-94.   

A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase.
Seamon KJ, Stivers JT.
J Biomol Screen. 2015 Jul;20(6):801-9.

ddpcRquant: threshold determination for single channel droplet digital PCR experiments.
Trypsteen W, Vynck M, De Neve J, Bonczkowski P, Kiselinova M, Malatinkova E, Vervisch K, Thas O, Vandekerckhove L, De Spiegelaere W.
Anal Bioanal Chem. 2015 Jul;407(19):5827-34.

June 2015

Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression.
Mbonye UR, Wang B, Gokulrangan G, Chance MR, Karn J.
Proteomics. 2015 Jun;15(12):2078-86.

Bone Marrow-Imprinted Gut-Homing of Plasmacytoid Dendritic Cells (pDCs) in Acute Simian Immunodeficiency Virus Infection Results in Massive Accumulation of Hyperfunctional CD4+ pDCs in the Mucosae.
Li H, Evans TI, Gillis J, Connole M, Reeves RK.
J Infect Dis. 2015 Jun 1;211(11):1717-25.
READ MORE: Are Early Immune Defenses Helping HIV Flourish?  

May 2015

Animal models in HIV-1 protection and therapy.
Hessell AJ, Haigwood NL.
Curr Opin HIV AIDS. 2015 May;10(3):170-6.

Viremic control and viral coreceptor usage in two HIV-1-infected persons homozygous for CCR5 Δ32.
Henrich TJ, Hanhauser E, Hu Z, Stellbrink HJ, Noah C, Martin JN, Deeks SG, Kuritzkes DR, Pereyra F.
AIDS. 2015 May 15;29(8):867-76.

HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.
Pino M, Erkizia I, Benet S, Erikson E, Fernández-Figueras MT, Guerrero D, Dalmau J, Ouchi D, Rausell A, Ciuffi A, Keppler OT, Telenti A, Kräusslich HG, Martinez-Picado J, Izquierdo-Useros N.
Retrovirology. 2015 May 7;12:37.

CD4 mimetics sensitize HIV-1-infected cells to ADCC.
Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy JP, Smith AB 3rd, Park J, Jones DM, Courter JR, Melillo BN, Kaufmann DE, Hahn BH, Permar SR, Haynes BF, Madani N, Sodroski JG, Finzi A.
Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94.
READ MORE: Exposing HIV-Infected Cells to Antibody Attack

Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.
Laird GM, Bullen CK, Rosenbloom DI, Martin AR, Hill AL, Durand CM, Siliciano JD, Siliciano RF.
J Clin Invest. 2015 May 1;125(5):1901-12.
READ MORE: To Reverse HIV Latency, Two Drugs Are Better Than One

Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR.
Sahu G, Farley K, El-Hage N, Aiamkitsumrit B, Fassnacht R, Kashanchi F, Ochem A, Simon GL, Karn J, Hauser KF, Tyagi M.
Virology. 2015 May 13;483:185-202.

April 2015

Molecular Determinants for Recognition of Divergent SAMHD1 Proteins by the Lentiviral Accessory Protein Vpx.
Schwefel D, Boucherit VC, Christodoulou E, Walker PA, Stoye JP, Bishop KN, Taylor IA.
Cell Host Microbe. 2015 Apr 8;17(4):489-99. 

Towards an HIV-1 cure: measuring the latent reservoir.
Bruner KM, Hosmane NN, Siliciano RF.
Trends Microbiol. 2015 Apr;23(4):192-203.
READ MORE: Better Tools Needed to Reach a Cure  

March 2015

T Memory Stem Cells and HIV: a Long-Term Relationship.
Chahroudi A, Silvestri G, Lichterfeld M.
Curr HIV/AIDS Rep. 2015 Mar;12(1):33-40. doi: 10.1007/s11904-014-0246-4.
READ MORE: Self-Sustaining Reservoirs of HIV  

February 2015

Select host restriction factors are associated with HIV persistence during antiretroviral therapy.
Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK.
AIDS. 2015 Feb 20;29(4):411-20
READ MORE: Restricting HIV Reservoir Size: Lessons from Patients

Accurate Quantification of Episomal HIV-1 Two-Long Terminal Repeat Circles by Use of Optimized DNA Isolation and Droplet Digital PCR.
Malatinkova E, Kiselinova M, Bonczkowski P, Trypsteen W, Messiaen P, Vermeire J, Verhasselt B, Vervisch K, Vandekerckhove L, De Spiegelaere W.
J Clin Microbiol. 2015 Feb;53(2):699-701.

January 2015

How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?
Ananworanich J, Dubé K, Chomont N.
Curr Opin HIV AIDS. 2015 Jan;10(1):18-28.
READ MORE: Boosting Killer T cells to Eliminate HIV Reservoirs

Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope.
Doores KJ, Kong L, Krumm SA, Le KM, Sok D, Laserson U, Garces F, Poignard P, Wilson IA, Burton DR.
J Virol. 2015 Jan 15;89(2):1105-18.
NB: acknowledgement correction including amfAR:

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF.
Nature. 2015 Jan 15;517(7534):381-5.
READ MORE: Boosting Killer T cells to Eliminate HIV Reservoirs  

December 2014

The Immunologic Effects of Mesalamine in Treated HIV-Infected Individuals with Incomplete CD4+ T Cell Recovery: A Randomized Crossover Trial.
Somsouk M, Dunham RM, Cohen M, Albright R, Abdel-Mohsen M, Liegler T, Lifson J, Piatak M, Gorelick R, Huang Y, Wu Y, Hsue PY, Martin JN, Deeks SG, McCune JM, Hunt PW.
PLoS One. 2014 Dec 29;9(12):e116306.  

Macrophage Infection via Selective Capture of HIV-1-Infected CD4(+) T Cells.
Baxter AE, Russell RA, Duncan CJ, Moore MD, Willberg CB, Pablos JL, Finzi A, Kaufmann DE, Ochsenbauer C, Kappes JC, Groot F, Sattentau QJ.
Cell Host Microbe. 2014 Dec 10;16(6):711-21.  

Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents.
Persaud D, Patel K, Karalius B, Rainwater-Lovett K, Ziemniak C, Ellis A, Chen YH, Richman D, Siberry GK, Van Dyke RB, Burchett S, Seage GR 3rd, Luzuriaga K; Pediatric HIV/AIDS Cohort Study.
JAMA Pediatr. 2014 Dec 1;168(12):1138-46. 

Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy.
Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK.
J Infect Dis. 2014 Dec 1;210(11):1838-43.  

Plasmacytoid Dendritic Cells from HIV-1 Elite Controllers Maintain a Gut-Homing Phenotype Associated with Immune Activation.
Li H, Goepfert P, Reeves RK.
AIDS Res Hum Retroviruses. 2014 Dec;30(12):1213-5.  

HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission.
Shen R, Raska M, Bimczok D, Novak J, Smith PD.
J Virol. 2014 Dec 15;88(24):14258-67.  

A primary CD4(+) T cell model of HIV-1 latency established after activation through the T cell receptor and subsequent return to quiescence.
Kim M, Hosmane NN, Bullen CK, Capoferri A, Yang HC, Siliciano JD, Siliciano RF.
Nat Protoc. 2014 Dec;9(12):2755-70.
READ MORE: Modeling and Controlling HIV  Reservoirs

Finding a Cure for Human Immunodeficiency Virus-1 Infection.
Blankson JN, Siliciano JD, Siliciano RF.
Infect Dis Clin North Am. 2014 Dec;28(4):633-650.  

Sulfonation pathway inhibitors block reactivation of latent HIV-1.
Murry JP, Godoy J, Mukim A, Swann J, Bruce JW, Ahlquist P, Bosque A, Planelles V, Spina CA, Young JA.
Virology. 2014 Dec;471-473:1-12.
READ MORE: Modeling and Controlling HIV  Reservoirs

November 2014

HIV-1 Envelope Glycoprotein Trimer Immunogenicity Elicited in the Presence of Human CD4 Alters the Neutralization Profile.
Forsell MN, McKee K, Feng Y, Mascola JR, Wyatt RT.
AIDS Res Hum Retroviruses. 2014 Nov;30(11):1089-98 

Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy.
Elliott JH, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron MJ, Smith MZ, Spelman T, McMahon J, Velayudham P, Brown G, Roney J, Watson J, Prince MH, Hoy JF, Chomont N, Fromentin R, Procopio FA, Zeidan J, Palmer S, Odevall L, Johnstone RW, Martin BP, Sinclair E, Deeks SG, Hazuda DJ, Cameron PU, Sékaly RP, Lewin SR.
PLoS Pathog. 2014 Nov 13;10(10):e1004473 

Cross-clade ultrasensitive PCR-based assays to measure HIV persistence in large-cohort studies.
Vandergeeten C, Fromentin R, Merlini E, Lawani MB, DaFonseca S, Bakeman W, McNulty A, Ramgopal M, Michael N, Kim JH, Ananworanich J, Chomont N.
J Virol. 2014 Nov;88(21):12385-96. 

HIV Type 1 (HIV-1) Proviral Reservoirs Decay Continuously Under Sustained Virologic Control in HIV-1-Infected Children Who Received Early Treatment.
Luzuriaga K, Tabak B, Garber M, Chen YH, Ziemniak C, McManus MM, Murray D, Strain MC, Richman DD, Chun TW, Cunningham CK, Persaud D.
J Infect Dis. 2014 Nov 15;210(10):1529-38.
READ MORE: The Impact of Early Treatment on HIV Reservoirs in Children  

October 2014

A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry.
Herschhorn A, Gu C, Espy N, Richard J, Finzi A, Sodroski JG.
Nat Chem Biol. 2014 Oct;10(10):845-52. 

CD4+ and CD8+ T Cell Activation Are Associated with HIV DNA in Resting CD4+ T Cells.
Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG.
PLoS One. 2014 Oct 23;9(10):e110731 
READ MORE: Sizing Up the HIV Reservoir

Hypogammaglobulinemia in BLT Humanized Mice - An Animal Model of Primary Antibody Deficiency
Martinez-Torres F, Nochi T, Wahl A, Garcia JV, Denton PW.
PLoS One. 2014 Oct 1;9(10):e108663.

September 2014

Lipopolysaccharide, immune activation, and liver abnormalities in HIV/hepatitis B virus (HBV)-coinfected individuals receiving HBV-active combination antiretroviral therapy.
Crane M, Avihingsanon A, Rajasuriar R, Velayudham P, Iser D, Solomon A, Sebolao B, Tran A, Spelman T, Matthews G, Cameron P, Tangkijvanich P, Dore GJ, Ruxrungtham K, Lewin SR.
J Infect Dis. 2014 Sep 1;210(5):745-51.

Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells.
Buzon MJ, Martin-Gayo E, Pereyra F, Ouyang Z, Sun H, Li JZ, Piovoso M, Shaw A, Dalmau J, Zangger N, Martinez-Picado J, Zurakowski R, Yu XG, Telenti A, Walker BD, Rosenberg ES, Lichterfeld M.
J Virol. 2014 Sep 1;88(17):10056-65.
READ MORE: Viral Reservoirs: How Low Must We Go?   

Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1.
Hill AL, Rosenbloom DI, Fu F, Nowak MA, Siliciano RF.
Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13475-80.
READ MORE: Viral Reservoirs: How Low Must We Go? 

The Histone Deacetylase Inhibitor Vorinostat (SAHA) Increases the Susceptibility of Uninfected CD4+ T Cells to HIV by Increasing the Kinetics and Efficiency of Postentry Viral Events.
Lucera MB, Tilton CA, Mao H, Dobrowolski C, Tabler CO, Haqqani AA, Karn J, Tilton JC.
J Virol. 2014 Sep 15;88(18):10803-12.

August 2014

Levels of circulating myeloid subpopulations and of heme oxygenase-1 do not predict CD4(+) T cell recovery after the initiation of antiretroviral therapy for HIV disease.
Seu L, Ortiz GM, Burt TD, Deeks SG, Martin JN, McCune JM.
AIDS Res Ther. 2014 Aug 5;11:27. 

Cutting Edge: An Antibody Recognizing Ancestral Endogenous Virus Glycoproteins Mediates Antibody-Dependent Cellular Cytotoxicity on HIV-1-Infected Cells.
Michaud HA, SenGupta D, de Mulder M, Deeks SG, Martin JN, Kobie JJ, Sacha JB, Nixon DF.
J Immunol. 2014 Aug 15;193(4):1544-8.
READ MORE: Innovative New Approaches to Designing HIV Vaccines

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection.
Raska M, Czernekova L, Moldoveanu Z, Zachova K, Elliott MC, Novak Z, Hall S, Hoelscher M, Maboko L, Brown R, Smith PD, Mestecky J, Novak J.
AIDS Res Ther. 2014 Aug 1;11:23.
READ MORE: Innovative New Approaches to Designing HIV Vaccines

The use of BLT mice to investigate the immune reconstitutionin the gastrointestinal tract.
Wahl A, Garcia JV. J Immunol Methods. 410:28-33.

July 2014

Immunologic strategies for HIV-1 remission and eradication.
Barouch DH, Deeks SG.
Science. 2014 Jul 11;345(6193):169-74. 

Programmed death-1 expression on CD4+ and CD8+ T cells in treated and untreated HIV disease.
Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG.
AIDS. 2014 Jul 31;28(12):1749-58.   

HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1.
Izquierdo-Useros N, Lorizate M, McLaren PJ, Telenti A, Kräusslich HG, Martinez-Picado J.
PLoS Pathog. 2014 Jul 17;10(7):e1004146  

Vaginal Myeloid Dendritic Cells Transmit Founder HIV-1.
Shen R, Kappes JC, Smythies LE, Richter HE, Novak L, Smith PD.
J Virol. 2014 Jul 1;88(13):7683-8.
READ MORE: Unraveling the Mechanisms of Male-to-Female HIV Transmission  

June 2014

Prevention of HIV-1 transmission with postexposure prophylaxis after inadvertent infected blood transfusion.
Al-Hajjar SH, Frayha HH, Al-Hazmi M, Batawi R, McIntosh K, Sax PE, Al-Thawadi S, Al-Jumaah S, Busch MP, Hanhauser E, Kuritzkes DR, Li JZ, Henrich TJ.
AIDS. 2014 Jun 19;28(10):1539-41.

A Cell-Intrinsic Inhibitor of HIV-1 Reverse Transcription in CD4(+) T Cells from Elite Controllers.
Leng J, Ho HP, Buzon MJ, Pereyra F, Walker BD, Yu XG, Chang EJ, Lichterfeld M.
Cell Host Microbe. 2014 Jun 11;15(6):717-28.
READ MORE:   How Cells Resist HIV Infection: New Clues

CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies.
Madani N, Princiotto AM, Schön A, LaLonde J, Feng Y, Freire E, Park J, Courter JR, Jones DM, Robinson J, Liao HX, Moody MA, Permar S, Haynes B, Smith AB 3rd, Wyatt R, Sodroski J.
J Virol. 2014 Jun 15;88(12):6542-6555.

Unraveling the relationship between microbial translocation and systemic immune activation in HIV infection.
Shan L, Siliciano RF.
J Clin Invest. 2014 Jun 2;124(6):2368-71.

Quantification of Integrated HIV DNA by Repetitive-Sampling Alu-HIV PCR on the Basis of Poisson Statistics.
De Spiegelaere W, Malatinkova E, Lynch L, Van Nieuwerburgh F, Messiaen P, O'Doherty U, Vandekerckhove L.
Clin Chem. 2014 Jun;60(6):886-95.

May 2014

An Example of Genetically Distinct HIV Type 1 Variants in Cerebrospinal Fluid and Plasma During Suppressive Therapy.
Dahl V, Gisslen M, Hagberg L, Peterson J, Shao W, Spudich S, Price RW, Palmer S.
J Infect Dis. 2014 May;209(10):1618-22.

HIV Antibody Characterization as a Method to Quantify Reservoir Size During Curative Interventions.
Burbelo PD, Bayat A, Rhodes CS, Hoh R, Martin JN, Fromentin R, Chomont N, Hütter G, Kovacs JA, Deeks SG.
J Infect Dis. 2014 May;209(10):1613-7.

HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality.
Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG.
PLoS Pathog. 2014 May 15;10(5):e1004078

Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission.
Yen PJ, Herschhorn A, Haim H, Salas I, Gu C, Sodroski J, Gabuzda D.
J Virol. 2014 May;88(9):5014-28.

Hepatitis C therapy with interferon-α and ribavirin reduces CD4 T-cell-associated HIV-1 DNA in HIV-1/hepatitis C virus-coinfected patients.
Sun H1, Buzon MJ, Shaw A, Berg RK, Yu XG, Ferrando-Martinez S, Leal M, Ruiz-Mateos E, Lichterfeld M.
J Infect Dis. 2014 May 1;209(9):1315-20.
READ MORE: Possible New Use for an Old Antiviral Drug in Attacking Latent HIV

BCA2/Rabring7 Targets HIV-1 Gag for Lysosomal Degradation in a Tetherin-Independent Manner.
Nityanandam R, Serra-Moreno R.
PLoS Pathog. 2014 May 22;10(5):e1004151

CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression.
Tabler CO, Lucera MB, Haqqani AA, McDonald DJ, Migueles SA, Connors M, Tilton JC.
J Virol. 2014 May;88(9):4976-86.

April 2014

New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo.
Bullen CK, Laird GM, Durand CM, Siliciano JD, Siliciano RF.
Nat Med. 2014 Apr;20(4):425-9.
READ MORE: Additional Approaches to Attacking the HIV Reservoir 

Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children.
Ananworanich J, Puthanakit T, Suntarattiwong P, Chokephaibulkit K, Kerr SJ, Fromentin R, Bakeman W, Intasan J, Mahanontharit A, Sirivichayakul S, Chomont N.
AIDS. 2014 Apr 24;28(7):1015-20.

Transcriptional control of HIV latency: Cellular signaling pathways, epigenetics, happenstance and the hope for a cure.
Mbonye U, Karn J.
Virology. 2014 Apr;454-455C:328-339.
READ MORE: Additional Approaches to Attacking the HIV Reservoir

Positive selection of primate genes that promote HIV-1 replication.
Meyerson NR, Rowley PA, Swan CH, Le DT, Wilkerson GK, Sawyer SL.
Virology. 2014 Apr;454-455:291-8.

A novel cell-based high-throughput screen for inhibitors of HIV-1 gene expression and budding identifies the cardiac glycosides.
Laird GM, Eisele EE, Rabi SA, Nikolaeva D, Siliciano RF.
J Antimicrob Chemother. 2014 Apr;69(4):988-94.
READ MORE: Additional Approaches to Attacking the HIV Reservoir 

Hepatitis C therapy with interferon-α and ribavirin reduces CD4 T-cell-associated HIV-1 DNA in HIV-1/hepatitis C virus-coinfected patients.
Sun H, Buzon MJ, Shaw A, Berg RK, Yu XG, Ferrando-Martinez S, Leal M, Ruiz-Mateos E, Lichterfeld M.
J Infect Dis. 2014 May 1;209(9):1315-20. doi: 10.1093/infdis/jit628. Epub 2013 Nov 25.

March 2014

A Pilot Study Assessing the Safety and Latency-Reversing Activity of Disulfiram in HIV-1-Infected Adults on Antiretroviral Therapy.
Spivak AM, Andrade A, Eisele E, Hoh R, Bacchetti P, Bumpus NN, Emad F, Buckheit R 3rd, McCance-Katz EF, Lai J, Kennedy M, Chander G, Siliciano RF, Siliciano JD, Deeks SG.
Clin Infect Dis. 2014 Mar;58(6):883-90
READ MORE: Testing “Shock and Kill” 

February 2014

Differential Blood and Mucosal Immune Responses against an HIV-1 Vaccine Administered via Inguinal or Deltoid Injection.
Yang OO, Ibarrondo FJ, Price C, Hultin LE, Elliott J, Hultin PM, Shih R, Hausner MA, Ng HL, Hoffman J, Jamieson BD, Anton PA.
PLoS One. 2014 Feb 18;9(2):e88621
READ MORE: HIV in the Blood and Gut: Exploring the Differences   

Discordance Between Peripheral and Colonic Markers of Inflammation During Suppressive ART.
Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM.
J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):133-41.  
READ MORE: HIV in the Blood and Gut: Exploring the Differences 

HIV-1 persistence in CD4(+) T cells with stem cell-like properties.
Buzon MJ, Sun H, Li C, Shaw A, Seiss K, Ouyang Z, Martin-Gayo E, Leng J, Henrich TJ, Li JZ, Pereyra F, Zurakowski R, Walker BD, Rosenberg ES, Yu XG, Lichterfeld M.
Nat Med. 2014 Feb;20(2):139-42. doi: 10.1038/nm.3445. Epub 2014 Jan 12. 

January 2014

Composition and Function of T Cell Subpopulations Are Slow to Change Despite Effective Antiretroviral Treatment of HIV Disease.
Emu B, Moretto WJ, Hoh R, Krone M, Martin JN, Nixon DF, Deeks SG, McCune JM.
PLoS One. 2014 Jan 21;9(1):e85613 

[The adaptation of lentiviruses to apes was a crucial step in the origin of HIV-1]. [Article in French]
Etienne L.
Med Sci (Paris). 2014 Jan;30(1):24-6

Susceptibility to CD8 T-Cell-Mediated Killing Influences the Reservoir of Latently HIV-1-Infected CD4 T Cells.
Buzon MJ, Yang Y, Ouyang Z, Sun H, Seiss K, Rogich J, Le Gall S, Pereyra F, Rosenberg ES, Yu XG, Lichterfeld M.
J Acquir Immune Defic Syndr. 2014 Jan 1;65(1):1-9.
READ MORE: Killer Immunity and HIV Reservoirs   

Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection.
Michaud HA, de Mulder M, Sengupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF.
Retrovirology. 2014 Jan 28;11(1):10. 

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells.
Shan L, Xing S, Yang HC, Zhang H, Margolick JB, Siliciano RF.
J Antimicrob Chemother. 2014 Jan;69(1):28-33.

A combination HIV reporter virus system for measuring post-entry event efficiency and viral outcome in primary CD4+ T cell subsets.
Tilton CA, Tabler CO, Lucera MB, Marek SL, Haqqani AA, Tilton JC.
J Virol Methods. 2014 Jan;195:164-9.

December 2013

Evans VA, Kumar N, Filali A, Procopio FA, Yegorov O, Goulet JP, Saleh S, Haddad EK, da Fonseca Pereira C, Ellenberg PC, Sekaly RP, Cameron PU, Lewin SR.
Myeloid Dendritic Cells Induce HIV-1 Latency in Non-proliferating CD4(+) T Cells.
PLoS Pathog. 2013 Dec;9(12):e1003799.
READ MORE: New Clues to the Nature of HIV Reservoirs

Josefsson L, von Stockenstrom S, Faria NR, Sinclair E, Bacchetti P, Killian M, Epling L, Tan A, Ho T, Lemey P, Shao W, Hunt PW, Somsouk M, Wylie W, Douek DC, Loeb L, Custer J, Hoh R, Poole L, Deeks SG, Hecht F, Palmer S.
The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time.
Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):E4987-96.
READ MORE: New Clues to the Nature of HIV Reservoirs  

November 2013

Hatano H, Strain MC, Scherzer R, Bacchetti P, Wentworth D, Hoh R, Martin JN, McCune JM, Neaton JD, Tracy RP, Hsue PY, Richman DD, Deeks SG.
Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial.
J Infect Dis. 2013 Nov 1;208(9):1436-42.
READ MORE: Building a Stronger HAART

Feng Y, Forsell MN, Flynn B, Adams W, Loré K, Seder R, Wyatt RT, Karlsson Hedestam GB.
Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants.
Virology. 2013 Nov;446(1-2):56-65.

Wohlfeiler D, Hecht J, Volk J, Fisher Raymond H, Kennedy T, McFarland W.
How Can We Improve Online HIV and STD Prevention for Men Who Have Sex with Men? Perspectives of Hook-Up Website Owners, Website Users, and HIV/STD Directors.
AIDS Behav. 2013 Nov;17(9):3024-33.

Persaud D, Gay H, Ziemniak C, Chen YH, Piatak M Jr, Chun TW, Strain M, Richman D, Luzuriaga K.
Absence of detectable HIV-1 viremia after treatment cessation in an infant.
N Engl J Med. 2013 Nov 7;369(19):1828-35.  

October 2013

Henrich TJ, Gandhi RT.
Early treatment and HIV-1 reservoirs: a stitch in time?
J Infect Dis. 2013 Oct 15;208(8):1189-93.
READ MORE: New Benefits of Antiretroviral Therapy Uncovered

Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, Shacklett BL, Wong JK, Deeks SG.
Prospective Antiretroviral Treatment of Asymptomatic, HIV-1 Infected Controllers.
PLoS Pathog. 2013 Oct;9(10):e1003691.
READ MORE: New Benefits of Antiretroviral Therapy Uncovered

All-trans-retinoic acid imprints expression of the gut-homing marker α4β7 while suppressing lymph node homing of dendritic cells.
Evans TI, Reeves RK
Clin Vaccine Immunol. 2013 Oct;20(10):1642-6.

September 2013

Breton G, Chomont N, Takata H, Fromentin R, Ahlers J, Filali-Mouhim A, Riou C, Boulassel MR, Routy JP, Yassine-Diab B, Sékaly RP.
Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection.
J Immunol. 2013 Sep 1;191(5):2194-204.
READ MORE: Attacking AIDS by Attacking Inflammation

August 2013

The mongoose, the pheasant, the pox, and the retrovirus.
Etienne L, Emerman M.
PLoS Biol. 2013;11(8):e1001641.

Lanxon-Cookson EC, Swain JV, Manocheewa S, Smith RA, Maust B, Kim M, Westfall D, Rolland M, Mullins JI.
Factors affecting relative fitness measurements in pairwise competition assays of human immunodeficiency viruses.
J Virol Methods. 2013 Aug 8;194(1-2):7-13.

Tan J, Sattentau QJ.
The HIV-1-containing macrophage compartment: a perfect cellular niche?
Trends Microbiol. 2013 Aug;21(8):405-12.
READ MORE: Exploring New Cell Reservoirs for HIV  

Cillo AR, Krishnan A, Mitsuyasu RT, McMahon DK, Li S, Rossi JJ, Zaia JA, Mellors JW.
Plasma viremia and cellular HIV-1 DNA persist despite autologous hematopoietic stem cell transplantation for HIV-related lymphoma.
J Acquir Immune Defic Syndr. 2013 Aug 1;63(4):438-41.

July 2013

Balazs AB, Bloom JD, Hong CM, Rao DS, Baltimore D.
Broad protection against influenza infection by vectored immunoprophylaxis in mice.
Nat Biotechnol. 2013 Jul;31(7):647-52.  

Klatt NR, Chomont N, Douek DC, Deeks SG.
Imune activation and HIV persistence: implications for curative approaches to HIV infection.
Immunol Rev. 2013 Jul;254(1):326-42.
READ MORE: Working Towards a Cure

Chang CC, Crane M, Zhou J, Mina M, Post JJ, Cameron BA, Lloyd AR, Jaworowski A, French MA, Lewin SR.
HIV and co-infections.
Immunol Rev. 2013 Jul;254(1):114-42.

Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM
Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism.
Sci Transl Med. 2013 Jul 10;5(193):193ra91.
READ MORE: Working Towards a Cure  

Hatano H, Jain V, Hunt PW, Lee TH, Sinclair E, Do TD, Hoh R, Martin JN, McCune JM, Hecht F, Busch MP, Deeks SG.
Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells.
J Infect Dis. 2013 Jul;208(1):50-6.
READ MORE: Working Towards a Cure   

Etienne L, Hahn BH, Sharp PM, Matsen FA, Emerman M.
Gene Loss and Adaptation to Hominids Underlie the Ancient Origin of HIV-1.
Cell Host Microbe. 2013 Jul 17;14(1):85-92. 

Forsell MN, Soldemo M, Dosenovic P, Wyatt RT, Karlsson MC, Karlsson Hedestam GB.
Independent Expansion of Epitope-Specific Plasma Cell Responses upon HIV-1 Envelope Glycoprotein Immunization.
J Immunol. 2013 Jul 1;191(1):44-51. 

Sandgren KJ, Smed-Sörensen A, Forsell MN, Soldemo M, Adams WC, Liang F, Perbeck L, Koup RA, Wyatt RT, Karlsson Hedestam GB, Loré K.
Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation.
J Immunol. 2013 Jul 1;191(1):60-9.  

Kulpa DA, Brehm JH, Fromentin R, Cooper A, Cooper C, Ahlers J, Chomont N, Sékaly RP.
The immunological synapse: the gateway to the HIV reservoir.
Immunol Rev. 2013 Jul;254(1):305-25.
READ MORE: Working Towards a Cure  

Mao Y, Wang L, Gu C, Herschhorn A, Désormeaux A, Finzi A, Xiang SH, Sodroski JG.
Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer.
Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12438-43.  

Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, Marozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, Khayat R, Deller MC, Clayton T, Tien H, Feizi T, Sanders RW, Paulson JC, Moore JP, Stanfield RL, Burton DR, Ward AB, Wilson IA
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Nat Struct Mol Biol. 2013 Jul;20(7):796-803.  

Serra-Moreno R, Zimmermann K, Stern LJ, Evans DT.
Tetherin/BST-2 Antagonism by Nef Depends on a Direct Physical Interaction between Nef and Tetherin, and on Clathrin-mediated Endocytosis.
PLoS Pathog. 2013 Jul;9(7):e1003487. 

Siliciano JD, Siliciano RF.
HIV-1 eradication strategies: design and assessment.
Curr Opin HIV AIDS. 2013 Jul;8(4):318-25.
READ MORE: Working Towards a Cure 

June 2013

Berro R, Yasmeen A, Abrol R, Trzaskowski B, Abi-Habib S, Grunbeck A, Lascano D, Goddard WA 3rd, Klasse PJ, Sakmar TP, Moore JP.
Use of G-Protein-Coupled and -Uncoupled CCR5 Receptors by CCR5 Inhibitor-Resistant and -Sensitive Human Immunodeficiency Virus Type 1 Variants.
J Virol. 2013 Jun;87(12):6569-81.
READ MORE: Purging Reservoirs of HIV

Henrich TJ, Hu Z, Li JZ, Sciaranghella G, Busch MP, Keating SM, Gallien S, Lin NH, Giguel FF, Lavoie L, Ho VT, Armand P, Soiffer RJ, Sagar M, Lacasce AS, Kuritzkes DR.
Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation.
J Infect Dis. 2013 Jun 1;207(11):1694-702.
READ MORE: Researcher Reports Two HIV Patients Showing No Signs of Virus in Wake of Stem-Cell Transplants
READ MORE: Purging Reservoirs of HIV  

Pace M, O'Doherty U.
Hematopoietic stem cells and HIV infection.
J Infect Dis. 2013 Jun 15;207(12):1790-2.

Pace MJ, Graf EH, O'Doherty U.
HIV 2-long terminal repeat circular DNA is stable in primary CD4+T Cells.
Virology. 2013 Jun 20;441(1):18-21.
READ MORE: Purging Reservoirs of HIV   

Josefsson L, Palmer S, Faria NR, Lemey P, Casazza J, Ambrozak D, Kearney M, Shao W, Kottilil S, Sneller M, Mellors J, Coffin JM, Maldarelli F.
Single Cell Analysis of Lymph Node Tissue from HIV-1 Infected Patients Reveals that the Majority of CD4(+) T-cells Contain One HIV-1 DNA Molecule.
PLoS Pathog. 2013 Jun;9(6):e1003432.  

Hunt PW, Shulman NS, Hayes TL, Dahl V, Somsouk M, Funderburg NT, McLaughlin B, Landay AL, Adeyemi O, Gilman LE, Clagett B, Rodriguez B, Martin JN, Schacker TW, Shacklett BL, Palmer S, Lederman MM, Deeks SG.
The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial.
Blood. 2013 Jun 6;121(23):4635-46.
READ MORE: Purging Reservoirs of HIV  

Shan L, Siliciano RF.
From reactivation of latent HIV-1 to elimination of the latent reservoir: the presence of multiple barriers to viral eradication.
Bioessays. 2013 Jun;35(6):544-52.
READ MORE: Purging Reservoirs of HIV  

Shan L, Rabi SA, Laird GM, Eisele EE, Zhang H, Margolick JB, Siliciano RF.
A novel PCR assay for quantification of HIV-1 RNA.
J Virol. 2013 Jun;87(11):6521-5.
READ MORE: Purging Reservoirs of HIV  

May 2013

Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, Palmer S, Pilcher C, Pillai S, Price RW, Rothenberger M, Schacker T, Siliciano J, Siliciano R, Sinclair E, Strain M, Wong J, Richman D, Deeks SG.
Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient.
PLoS Pathog. 2013 May;9(5):e1003347.
READ MORE: Multi-Targeted Approaches to an HIV Cure  

Vandergeeten C, Fromentin R, Dafonseca S, Lawani MB, Sereti I, Lederman MM, Ramgopal M, Routy JP, Sékaly RP, Chomont N.
Interleukin-7 promotes HIV persistence during antiretroviral therapy.
Blood. 2013 May 23;121(21):4321-9.  

Bartholomeeusen K, Fujinaga K, Xiang Y, Peterlin BM.
Histone Deacetylase Inhibitors (HDACis) That Release the Positive Transcription Elongation Factor b (P-TEFb) from Its Inhibitory Complex Also Activate HIV Transcription.
J Biol Chem. 2013 May 17;288(20):14400-7.
READ MORE: Multi-Targeted Approaches to an HIV Cure

Hatano H.
Immune activation and HIV persistence: considerations for novel therapeutic interventions.
Curr Opin HIV AIDS. 2013 May;8(3):211-6.
READ MORE: Multi-Targeted Approaches to an HIV Cure

Stone D, Kiem HP, Jerome KR.
Targeted gene disruption to cure HIV.
Curr Opin HIV AIDS. 2013 May;8(3):217-23.
READ MORE: Multi-Targeted Approaches to an HIV Cure

Walsh AD, Bimber BN, Das A, Piaskowski SM, Rakasz EG, Bean AT, Mudd PA, Ericsen AJ, Wilson NA, Hughes AL, O'Connor DH, Maness NJ.
Acute Phase CD8+ T Lymphocytes against Alternate Reading Frame Epitopes Select for Rapid Viral Escape during SIV Infection.
PLoS One. 2013 May 6;8(5):e61383.  

Mbonye UR, Gokulrangan G, Datt M, Dobrowolski C, Cooper M, Chance MR, Karn J.
Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4(+) T Lymphocytes.
PLoS Pathog. 2013 May;9(5):e1003338

April 2013

McNatt MW, Zang T, Bieniasz PD.
Vpu binds directly to tetherin and displaces it from nascent virions.
PLoS Pathog. 2013 Apr;9(4):e1003299. 

Voit RA, McMahon MA, Sawyer SL, Porteus MH.
Generation of an HIV Resistant T-cell Line by Targeted "Stacking" of Restriction Factors.
Mol Ther. 2013 Apr;21(4):786-95
READ MORE: Stopping HIV Using a Cocktail of Genes Rather than Drugs 

March 2013

Désormeaux A, Coutu M, Medjahed H, Pacheco B, Herschhorn A, Gu C, Xiang SH, Mao Y, Sodroski J, Finzi A.
The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.
J Virol. 2013 Mar;87(5):2549-62.  

Kutluay SB, Perez-Caballero D, Bieniasz PD.
Fates of Retroviral Core Components during Unrestricted and TRIM5-Restricted Infection.
PLoS Pathog. 2013 Mar;9(3):e1003214. 

Palmer S.
Advances in detection and monitoring of plasma viremia in HIV-infected individuals receiving antiretroviral therapy.
Curr Opin HIV AIDS. 2013 Mar;8(2):87-92. 
READ MORE: Perfecting Tools to Monitor HIV Viral Loads

February 2013

Dunham RM, Gordon SN, Vaccari M, Piatak M, Huang Y, Deeks SG, Lifson J, Franchini G, McCune JM.
Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase.
AIDS Res Hum Retroviruses. 2013 Feb;29(2):207-14.
READ MORE: Keeping Track of HIV Reservoirs

Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, Wong J, Johnston R, Siliciano RF, Richman DD, O'Doherty U, Palmer S, Deeks SG, Siliciano JD.
Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies.
PLoS Pathog. 2013 Feb;9(2):e1003174. 
READ MORE: Keeping Track of HIV Reservoirs  

January 2013

Ross MW, Nyoni J, Bowen AM, Williams ML, Kashiha JJ.
Sexual and geographic organization of men who have sex with men in a large East African city: opportunities for outreach.
BMJ Open. 2012 Nov 22;2(6) e001813.  

Azzoni L, Foulkes AS, Papasavvas E, Mexas AM, Lynn KM, Mounzer K, Tebas P, Jacobson JM, Frank I, Busch MP, Deeks SG, Carrington M, O'Doherty U, Kostman J, Montaner LJ.
Pegylated Interferon Alfa-2a Monotherapy Results in Suppression of HIV Type 1 Replication and Decreased Cell-Associated HIV DNA Integration.
J Infect Dis. 2013 Jan; 207(2):213-22.
READ MORE: Controlling HIV After Stopping Antiretroviral Therapy