amfAR, The Foundation for AIDS Research

Request for Proposals

Impact Grants: Gaining Insights from the Clinic

Registration Deadline: Friday, April 6, 2018 12:00 PM Eastern Time

Registration is REQUIRED (click here)

LOI Submission Deadline: Wednesday, April 11, 2018 3:00 PM Eastern Time  

The goal of this RFP is to generate practical, implementable information that will facilitate the design and interpretation of broadly generalizable HIV cure clinical research.

Specific areas of interest

1. Identify pre-ATI predictors of post-treatment control (PTC) or delay to rebound

2. Diversify the HIV cure clinical study population

Funding Opportunities

1.1: Meta-analysis of data from completed clinical trials (1 year; Total Costs: $100,000)

1.2: Addition of study arm to an existing clinical trial (4 years; Total Costs: $300,000)

1.3: Addition of reservoir and outcome (PTC or delay to rebound) analyses to an existing clinical trial (4 years; Total Costs: $100,000)

2.1: Addition of a recruitment and retention intervention to an existing clinical trial (4 years; Total Costs: $50,000)

2.2: Characterization of clinical case studies (1 year; Total Costs: $75,000)

2.3: Characterization of the reservoir in LMIC settings (2 years; Total Costs: $50,000)


Researchers holding a doctoral degree and affiliated with a nonprofit research institution are eligible to apply. Areas of interest 1.1, 1.2, 1.3, 2.1, and 2.2 are open to investigators from any region of the world. Area of interest 2.3 is open only to principal investigators based in low-, lower-middle-, or upper-middle-income economy countries as defined by the World Bank.

Links to Additional Information about this RFP

Detailed Information about Funding Opportunities

Eligibility Information

Letter of Intent Components

Important Dates, Submission, Review and Approval Pipeline

Grant Policies

Click here for a PDF of the entire RFP