Research News 3
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The Issue of Tissue: Getting to the Source of the HIV Reservoir
Researchers emphasize a full characterization of the HIV reservoir needs to focus on tissue sites, not only blood, in the search for a cure.
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Improving HIV Latency-Reversing Strategies
Laying the groundwork for a cure, researchers investigate a potent “pathogen-activated” antiretroviral therapy strategy to eliminate HIV reservoirs.
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Developing the Next Generation of COVID-19 Vaccines
Researchers have again parlayed HIV research to COVID-19 to develop a nanoparticle mRNA-based vaccine platform to address SARS-CoV-2 variants.
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New Case of HIV Cure Reported
A fourth person, dubbed the City of Hope patient, has achieved HIV remission following a transplant using stem cells with a CCR5delta32 mutation.
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Dr. Steven Deeks Receives Mentoring Honor
University of California, San Francisco, recognizes Steven Deeks, amfAR Institute for HIV Cure Research principal investigator, for his mentoring work.
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Dismantling HIV Silencing Factors
Dr. Ya-Chi Ho and team focus on dismantling SLTM, an HIV silencing factor, in order to reactivate HIV in reservoirs for the virus to be targeted.
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New Chair Appointed to amfAR’s Scientific Advisory Committee
Dr. Lishomwa Ndhlovu, an HIV researcher and director of the Ndhlovu Laboratory, has been appointed as the new chair of amfAR’s Scientific Advisory Committee.
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Refining COVID-19 Vaccines and Implications for PLWH
To refine established and new COVID-19 vaccine products as SARS-CoV-2 evolves, researchers seek the best viral targets by studying antibody responses.
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New Hope for an HIV Vaccine?
On HIV Vaccine Awareness Day, amfAR applauds researchers like Aleksandar Antanasijevic who are bringing us one step closer to preventive HIV vaccines.
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Identifying New Targets in Host Cells to Attack HIV
By examining genes, researchers identify new host cell factors to target in order to interrupt HIV replication in primary CD4+ T cells.
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Using PET Scans to Visualize HIV
ImmunoPET imaging, using PET scans with a zirconium-89 tracer, allows researchers to find HIV in patients’ organs and tissues that would be invasive to sample.
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Defining Targets for Eradicating Latent HIV Reservoirs
Researchers find evidence that effector memory T cells are a key component of HIV reservoir and suggest Nef as a potential therapeutic target.
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Shock-and-Kill Trial Falls Short
Research Question One of the most studied paradigms to cure HIV is the so-called shock-and-kill approach, in which dormant HIV is “shocked” by a latency-reversing agent (LRA) into making copies of itself and thus alerting the immune system to its presence, while boosting the ability of the immune system to kill infected cells. To date,…
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Researchers Report Potential New Case of HIV Cure
A woman shows no signs of HIV after receiving a stem cell transplant using cord blood stem cells to treat her leukemia.