Publications from amfAR Grantees and Fellows

Introduction

Each month, the findings of amfAR-funded researchers (names in bold) are published in peer-reviewed journals, which are listed below by month of publication. In each case you can click on the “ABSTRACT” link for a brief summary of the research paper as it appears in the journal. In some cases, you can click on the “READ MORE” link to access related articles written for a lay audience by amfAR staff.

2025 | 2024 | 2023 | 2022 | 2021 | 2020

January 2026

HIV-specific CD8+ T-cell proliferative response 24 weeks after early antiretroviral therapy initiation is associated with the subsequent reduction in the viral reservoir.
van Paassen PM, Pasternak AO, Bolluyt DC, van Dort KA, van Nuenen AC, Maurer I, Boeser-Nunnink B, Buchholtz NVEJ, Mahmoudi T, Lungu C, van Crevel R, Rokx C, Symons J, Nijhuis M, van der Veen ALIP, Vogt L, Klouwens MJ, Prins JM, Kootstra NA, de Bree GJ. Elife. 2026 Jan 23;14:RP106402. doi: 10.7554/eLife.106402.
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Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV.
Fombellida-Lopez C, Valaitienė A, Winchester L, Maes N, Dellot P, Vanwinge C, Ladang A, Cavalier E, Susin F, Vaira D, Hayette MP, Reenaers C, Moutschen M, Fletcher CV, Pasternak AO, Darcis G. Elife. 2026 Jan 23;14:RP106931. doi: 10.7554/eLife.106931.

December 2025

Correlates of HIV-1 control after combination immunotherapy.
Peluso MJ, Sandel DA, Deitchman AN, Kim SJ, Dalhuisen T, Tummala HP, Tibúrcio R, Zemelko L, Borgo GM, Singh SS, Schwartz K, Deswal M, Williams MC, Hoh R, Shimoda M, Narpala S, Serebryannyy L, Khalili M, Vendrame E, SenGupta D, Whitmore LS, Tisoncik-Go J, Gale M Jr, Koup RA, Mullins JI, Felber BK, Pavlakis GN, Reeves JD, Petropoulos CJ, Glidden DV, Spitzer MH, Gama L, Caskey M, Nussenzweig MC, Chew KW, Henrich TJ, Yukl SA, Cohn LB, Deeks SG, Rutishauser RL. Nature. 2025 Dec 1.
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RXFP1, the relaxin receptor: Lost and found in translation.
Lal M, Eddy S, Walentinsson A, Hodgin JB, Hansen PBL, Althage M, Kretzler M. Drug Discov Today. 2025 Nov;30(11):104483. doi: 10.1016/j.drudis.2025.104483.

Immunotherapy and impact on tissue reservoirs.
King HAD, AngIelovich TA, Moso MA, Pascoe RD, Churchill MJ, Lewin SR. Curr Opin HIV AIDS. 2025 Nov 21;21(1):31-9. doi: 10.1097/COH.0000000000000996.

Humanized DRAGA mice are a valuable model to study novel immunotherapies for HIV-1.
Pumtang-On P, Thron LK, Goodarzi N, Davey BC, Sevcik EN, Coleman-Fuller N, Karim AF, Vezys V, Rao M, Moriarity BS, Pampusch MS, Rendahl AK, Casares SA, Skinner PJ. J Immunol. 2025 Nov 1;214(11):3017-3027.

November 2025

HIV-1 envelope trimer vaccine induces sex-associated differences in antibody responses: a phase 1 clinical trial.
Reiss EIMM, van der Straten K, Graus LTM, Grobben M, Vlaming KE, van der Veen AIP, Liesdek MH, Ozorowski G, Corcoran M, Gao H, Greene KM, Yates NL, Sawant S, Kerster G, Burger JA, Schonherr S, Cheeseman HM, Evans A, McFarlane LR, Tran AS, Torres JL, Lin RN, Jo G, Tolazzi M, Mundsperger P, Katinger D, Cupo A, Moore JP, Hurks R, Vogt L, Soeters MR, Kootstra NA, Scarlatti G, Tomaras GD, Montefiori DC, Karlsson Hedestam GB, Ward AB, Klouwens M, de Jong MD, Prins JM, Claireaux M, Geijtenbeek TBH, Shattock RJ, van Gils MJ, Sanders RW, de Bree GJ. Nat Commun. 2025 Nov 21;16(1):10250.

October 2025

Local structural flexibility drives oligomorphism in computationally designed protein assemblies.
Khmelinskaia A, Bethel NP, Fatehi F, Mallik BB, Antanasijevic A, Borst AJ, Lai SH, Chim HY, Wang JY’, Miranda MC, Watkins AM, Ogohara C, Caldwell S, Wu M, Heck AJR, Veesler D, Ward AB, Baker D, Twarock R, King NP. Nat Struct Mol Biol. 2025 Jun;32(6):1050-1060.

Fostemsavir analog BMS-818251 has enhanced viral neutralization potency and similar escape mutation profile.
Lai Y-T, Dingens AS, DeMouth M, Helmold Hait S, O’Dell S, Schon A, Olia AS, Wang T, Shrader HR, Lovelace SE, Pegu A, Doria-Rose NA, Mascola JR, Bloom JD, Kwong PD. Antimicrob Agents Chemother. 2025 Oct;69(10):e0191024

Viral reservoir characteristics in lymphoid tissues of HIV-1 elite controllers.
Marzi SK, Naasz CM, Carrere L, Gasca-Capote C, Roseto IC, Gao C, Cavassini M, Mastrangelo A, Lichterfeld M, Perreau M, Yu XG. JCI Insight. 2025 Oct 28:e197308.
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September 2025

Sex differences in HIV-1 reservoir cell selection are linked to altered innate immune profiles.
Tan TS, Gao C, Hochroth AS, Vela L, Carrere L, Kalavacherla S, Hong S, Lancien M, Naasz CM, Niesar A, Marzi SK, Roseto IC, Bone B, Lian X, Yuki Y, Viard M, Hoh R, McMahon DK, Bosch RJ, Kassaye SG, Gandhi RT, Carrington M, Deeks SG, Tien PC, Peluso MJ, Jacobson JM, Lichterfeld M, Yu XG. Sci Transl Med. 2025 Sep 17;17(816):eadu7154. doi: 10.1126/scitranslmed.adu7154. Epub 2025 Sep 17.
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August 2025

Differential decreases in various HIV DNA regions and HIV transcripts after ART initiation during chronic infection.
Janssens J, Isbell C, Kim SJ, Wedrychowski A, Barbehenn A, Hoh R, Pillai SK, Peluso MJ, Lee SA, Henrich TJ, Roan NR, Deeks SG, Yukl SA. J Virol. 2025 Aug 19;99(8):e0068325. doi: 10.1128/jvi.00683-25. Epub 2025 Jul 8.

Long-term effect of temporary ART initiated during primary HIV-1 infection on viral persistence.
Pasternak AO, van Paassen PM, Verschoor YL, Vroom J, van Dort KA, Maurer I, Grijsen ML, Wit FW, de Bree GJ, Kootstra NA, Prins JM, Berkhout B. Nat Commun. 2025 Jul 30;16(1):6989. doi: 10.1038/s41467-025-62362-0.
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No associations between HIV reservoir and inflammation in long-term virally suppressed dolutegravir-based ART-treated individuals.
Fombellida-Lopez C, Aguilar Ortmans D, Moutschen M, Pasternak AO, Darcis G. Front Immunol. 2025 Jul 28;16:1628086. doi: 10.3389/fimmu.2025.1628086. eCollection 2025.

July 2025

Applications and limitations of the passenger hypothesis for HIV reservoir persistence and cure.
Schiffer JT, Mudd JC, Antar AAR, Spivak AM, Reeves DB. J Virol. 2025 Jul 22;99(7):e0071425. doi: 10.1128/jvi.00714-25.

June 2025

Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations.
Tenthorey JL, Del Banco S, Ramzan I, Klingenberg H, Liu C, Emerman M, Malik HS. Cell Genom. 2025 Jun 11;5(6):100818. doi: 10.1016/j.xgen.2025.100818. Epub 2025 Mar 25.

Targeting Ikaros and Aiolos with pomalidomide fails to reactivate or induce apoptosis of the latent HIV reservoir.
Pascoe RD, Kim Y, Rhodes A, Ong J, Tumpach C, Gubser C, Chang JJ, McMahon JH, Lewin SR, Rasmussen TA. J Virol. 2025 Mar 18;99(3):e0167624.2025

May 2025

Efficient mRNA delivery to resting T cells to reverse HIV latency.
Cevaal PM, Kan S, Fisher BM, Moso MA, Tan A, Liu H, Ali A, Tanaka K, Shepherd RA, Kim Y, Ong J, Furtado DL, Holz M, Purcell DFJ, Casan JML, Payne T, Zhao W, Fareh M, McMahon JH, Deeks SG, Hoh R, Telwatte S, Pouton CW, Johnston APR, Caruso F, Symons J, Lewin SR, Roche M. Nat Commun. 2025 May 29;16(1):4979. doi: 10.1038/s41467-025-60001-2.
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Anti-HIV-1 HSPC-based gene therapy with safety kill switch to defend against and attack HIV-1 infection.
Guo Q, Parikh K, Zhang J, Brinkley A, Chen G, Jakramonpreeya N, Zhen A, An DS. Mol Ther: Methods Clin Develop. 2025 June; 33. doi.org/10.1016/j.omtm.2025.101486.
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April 2025

Design and Characterization of Inhibitors of Cell-Mediated Degradation of APOBEC3G That Decrease HIV-1 Infectivity.
Sawyer AM, Vaca CC, Malik N, Clerc I, Craft J, Hudson H, Scholtés GK, Schiltz GE, Roh M, Song C, D’Aquila RT. Viruses. 2025 Apr 1;17(4):514.
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Transcriptomic profiling of severe and critical COVID-19 patients reveals alterations in expression, splicing and polyadenylation.
Labrecque M, Brunet-Ratnasingham E, Hamilton LK, Auld D, Montpetit A, Richards B, Durand M, Rousseau S, Finzi A, Kaufmann DE, Tetreault M. Sci Rep. 2025 Apr 18;15(1):13469.
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March 2025

Afucosylated broadly neutralising antibodies targeting HIV envelope elicit enhanced NK cell-mediated cytotoxicity against HIV-infected CD4+ T cell and macrophage targets.
Wilhelm O, Jordan C, Kek H, Brunton-O’Sullivan MM, Rikard-Bell L, Ramanathan P, Chung AW, Poumbourios P, Wines BD, Jaworowski A, Hearps AC. J Leukoc Biol. 2025 Mar 15:qiaf033. doi: 10.1093/jleuko/qiaf033.

Phenotyping Viral Reservoirs to Reveal HIV-1 Hiding Places.
Chen W, Berkhout B, Pasternak AO. Curr HIV/AIDS Rep. 2025 Feb 4;22(1):15.
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Longitudinal changes in the transcriptionally active and intact HIV reservoir after starting ART during acute infection.
Janssens J, Wedrychowski A, Kim SJ, Isbell C, Hoh R, Pillai SK, Henrich TJ, Deeks SG, Roan NR, Lee SA, Yukl SA.J Virol. 2025 Mar 18;99(3):e0143124. doi: 10.1128/jvi.01431-24. Epub 2025 Feb 5.

February 2025

Lessons Learned in Eliciting Systematic Participant Perspectives in a Combination HIV Cure Research Trial.
Dubé K, Patel H, Meanley S, Dee L, Korolkova A, Wan F, Eskaf S, Williams M, Hoh R, Deeks SG, Peluso MJ, Sugarman J, Sauceda JA. AIDS Res Hum Retroviruses. 2025 Feb 5. doi: 10.1089/aid.2024.0086.
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Rapamycin enhances CAR-T control of HIV replication and reservoir elimination in vivo
Mu W, Tomer S, Harding J, Kedia N, Rezek V, Cook E, Patankar V, Carrillo MA, Martin H, Ng H, Wang L, Marsden MD, Kitchen SG, Zhen A. J Clin Invest. 2025 Feb 11. doi: 10.1172/JCI185489

January 2025

Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes.
Langley CA, Dietzen PA, Emerman M, Tenthorey JL, Malik HS. bioRxiv [Preprint]. 2024 Aug 17:2024.08.06.606855. doi: 10.1101/2024.08.06.606855. Update in: Proc Natl Acad Sci U S A. 2025 Jan 28;122(4):e2416811122. doi: 10.1073/pnas.2416811122.

Anti-immune complex antibodies are elicited during repeated immunization with HIV Env immunogens.
Brown S, Antanasijevic A, Sewall LM, Garcia DM, Brouwer PJM, Sanders RW, Ward AB. Sci Immunol. 2025 Jan 17;10(103):eadp5218.

Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective studies.
Gunst JD, Gohil J, Li JZ, Bosch RJ, White Catherine Seamon A, Chun TW, Mothe B, Gittens K, Praiss L, De Scheerder MA, Vandekerckhove L, Escandón K, Thorkelson A, Schacker T, SenGupta D, Brander C, Papasavvas E, Montaner LJ, Martinez-Picado J, Calin R, Castagna A, Muccini C, de Jong W, Leal L, Garcia F, Gruters RA, Tipoe T, Frater J, Søgaard OS, Fidler S. Nat Commun. 2025 Jan 21;16(1):906.
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December 2024

Post-intervention control in HIV immunotherapy trials.
Sandel DA, Rutishauser RL, Peluso MJ. Curr Opin HIV AIDS. 2025 Jan 1;20(1):70-79. doi: 10.1097/COH.0000000000000890. Epub 2024 Nov 4.
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November 2024

Plant-produced SARS-CoV-2 antibody engineered towards enhanced potency and in vivo efficacy.
de Taeye SW, Faye L, Morel B, Schriek AI, Umotoy JC, Yuan M, Kuzmina NA, Turner HL, Zhu X, Grünwald-Gruber C, Poniman M, Burger JA, Caniels TG, Fitchette AC, Desgagnés R, Stordeur V, Mirande L, Beauverger G, de Bree G, Ozorowski G, Ward AB, Wilson IA, Bukreyev A, Sanders RW, Vezina LP, Beaumont T, van Gils MJ, Gomord V. Plant Biotechnol J. 2024 Nov 19. doi: 10.1111/pbi.14458. Online ahead of print.

Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease.
Barbehenn A, Shi L, Shao J, Hoh R, Hartig HM, Pae V, Sarvadhavabhatla S, Donaire S, Sheikhzadeh C, Milush J, Laird GM, Mathias M, Ritter K, Peluso MJ, Martin J, Hecht F, Pilcher C, Cohen SE, Buchbinder S, Havlir D, Gandhi M, Henrich TJ, Hatano H, Wang J, Deeks SG, Lee SA. Nat Commun. 2024 Nov 18;15(1):9966.

Footprints of innate immune activity during HIV-1 reservoir cell evolution in early-treated infection.
Sun W, Gao C, Gladkov GT, Roseto I, Carrere L, Parsons EM, Gasca-Capote C, Frater J, Fidler S, Yu XG, Lichterfeld M; RIVER Trial Study Group. J Exp Med. 2024 Nov 4;221(11):e20241091. doi: 10.1084/jem.20241091.

Profound reduction of HIV-1 reservoir cells over three decades of antiretroviral therapy started in early infancy.
Vela LC, Carrere L, Naasz C, Kalavacherla S, Tan TS, de Armas L, Gao C, Yu XG, Pahwa SG, Luzuriaga K, Lichterfeld M. JCI Insight. 2024 Nov 14:e186550. doi: 10.1172/jci.insight.186550. Online ahead of print.
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October 2024

Inhibition of HIV-1 replication by nanobodies targeting tetraspanin CD9.
Umotoy JC, Kroon PZ, Man S, van Dort KA, Atabey T, Schriek AI, Dekkers G, Herrera-Carrillo E, Geijtenbeek TBH, Heukers R, Kootstra NA, van Gils MJ, de Taeye SW. iScience. 2024 Sep 13;27(10):110958.
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Functional comparison of Fc-engineering strategies to improve anti-HIV-1 antibody effector functions.
Schriek AI, Falck D, Wuhrer M, Kootstra NA, van Gils MJ, de Taeye SW. Antiviral Res. 2024 Sep 27;231:106015.

September 2024

Galectin-9 Levels as a Potential Predictor of Intact HIV Reservoir Decay.
Serrano-Villar S, Gala A, Bacchetti P, Hoh R, di Germanio C, Cohn LB, Henrich TJ, Hunt PW, Laird GM, Pillai SK, Deeks SG, Peluso MJ. J Infect Dis. 2024 Aug 28:jiae426. doi: 10.1093/infdis/jiae426.
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August 2024

Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies.
Parthasarathy D, Pothula KR, Dam KA, Ratnapriya S, Benet HC, Parsons R, Huang X, Sammour S, Janowska K, Harris M, Sacco S, Sodroski J, Bridges MD, Hubbell WL, Acharya P, Herschhorn A. Nat Commun. 2024 Aug 26;15(1):7334.

Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells.
Sáez-Cirión A, Mamez AC, Avettand-Fenoel V, Nabergoj M, Passaes C, Thoueille P, Decosterd L, Hentzien M, Perdomo-Celis F, Salgado M, Nijhuis M, Melard A, Gardiennet E, Lorin V, Monceaux V, Chapel A, Gourves M, Lechartier M, Mouquet H, Wensing A, Picado JM, Yerly S, Rougemont M, Calmy A. Nat Med. 2024 Sep 2. doi: 10.1038/s41591-024-03277-z.
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Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through cell-mediated killing.
de Taeye SW, Schriek AI, Umotoy JC, Grobben M, Burger JA, Sanders RW, Vidarsson G, Wuhrer M, Falck D, Kootstra NA, van Gils MJ. Commun Biol. 2024 Aug 9;7(1):964. doi: 10.1038/s42003-024-06659-8.

July 2024

Priming antibody responses to the fusion peptide in rhesus macaques.
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Allen JD, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB. NPJ Vaccines. 2024 Jul 12;9(1):126.

SMD9L acts as an antiviral factor against HIV-1 and primate lentiviruses by restricting viral and cellular translation.
Legrand A, Dahoui C, De La Myre Mory C, Noy K, Guiguettaz L, Versapuech M, Loyer C, Pillon M, Wcislo M, Guéguen L, Berlioz-Torrent C, Cimarelli A, Mateo M, Fiorini F, Ricci EP,Etienne L. PLoS Biol. 2024 Jul 3;22(7):e3002696.
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June 2024

Mapping the Evolutionary Space of SARS-CoV-2 Variants to Anticipate Emergence of Subvariants Resistant to COVID-19 Therapeutics.
Rojas Chávez RA, Fili M, Han C, Rahman SA, Bicar IGL, Gregory S, Helverson A, Hu G, Darbro BW, Das J, Brown GD, Haim H. PLoS Comput Biol. 2024 Jun 10;20(6):e1012215.

Impact of variable sampling on estimates of HIV-1 reservoir formation dates.
Kankaka EN, Poon AFY, Quinn TC, Chang LW, Prodger JL, Redd AD. J Infect Dis. 2024 May 31:jiae294. doi: 10.1093/infdis/jiae294. Online ahead of print.
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May 2024

Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity.
Brunet-Ratnasingham E, Morin S, Randolph HE, Labrecque M, Bélair J, Lima-Barbosa R, Pagliuzza A, Marchitto L, Hultström M, Niessl J, Cloutier R, Sreng Flores AM, Brassard N, Benlarbi M, Prévost J, Ding S, Anand SP, Sannier G, Marks A, Wågsäter D, Bareke E, Zeberg H, Lipcsey M, Frithiof R, Larsson A, Zhou S, Nakanishi T, Morrison D, Vezina D, Bourassa C, Gendron-Lepage G, Medjahed H, Point F, Richard J, Larochelle C, Prat A, Cunningham JL, Arbour N, Durand M, Richards JB, Moon K, Chomont N, Finzi A, Tétreault M, Barreiro L, Wolf G, Kaufmann DE. Nat Commun. 2024 May 16;15(1):4177.

Dynamics of virological and immunological markers of HIV persistence after allogeneic haematopoietic stem-cell transplantation in the IciStem cohort: a prospective observational cohort study. Salgado M, Gálvez C, Nijhuis M, Kwon M, Cardozo-Ojeda EF, Badiola J, Gorman MJ, Huyveneers LEP, Urrea V, Bandera A, Jensen BO, Vandekerckhove L, Jurado M, Raj K, Schulze Zur Wiesch J, Bailén R, Eberhard JM, Nabergoj M, Hütter G, Saldaña-Moreno R, Oldford S, Barrett L, Ramirez MLM, Garba S, Gupta RK, Revollo B, Ferra-Coll C, Kuball J, Alter G, Sáez-Cirión A, Diez-Martin JL, Duke ER, Schiffer JT, Wensing A, Martinez-Picado J; IciStem Consortium.Lancet HIV. 2024 Jun;11(6):e389-e405.
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April 2024

Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease
Barbehenn A, Shi L, Shao J, Hoh R, Hartig HM, Pae V, Sarvadhavabhatla S, Donaire S, Sheikhzadeh C, Milush J, Laird GM, Mathias M, Ritter K, Peluso M, Martin J, Hecht F, Pilcher C, Cohen SE,
Buchbinder S, Havlir D, Gandhi M, Henrich TJ, Hatano H, Wang J, Deeks SG, Lee SA. Rapid Biphasic Decay of Intact and Defective HIV DNA Reservoir During Acute Treated HIV Disease. medRxiv [Preprint]. 2024 Mar 28:2024.03.27.24304867. doi: 10.1101/2024.03.27.24304867.
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March 2024

Effective and targeted latency reversal in CD4(+) T cells from individuals on long term combined antiretroviral therapy initiated during chronic HIV-1 infection.
Ngo MH, Pankrac J, Ho RCY, Ndashimye E, Pawa R, Ceccacci R, Biru T, Olabode AS, Klein K, Li Y, Kovacs C, Assad R, Jacobson JM, Canaday DH, Tomusange S, Jamiru S, Anok A, Kityamuweesi T, Buule P, Galiwango RM, Reynolds SJ, Quinn TC, Redd AD, Prodger JL, Mann JFS, Arts EJ. Emerg Microbes Infect. 2024 Dec;13(1):2327371.
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Influence of Amino Acid Substitutions in Capsid Proteins of Coxsackievirus B5 on Free Chlorine and Thermal Inactivation.
Torii S, Gouttenoire J, Kumar K, Antanasijevic A, Kohn T. Environ Sci Technol. 2024 Mar 26;58(12):5279-5289. doi: 10.1021/acs.est.3c10409. Epub 2024 Mar 15.

Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells.
Carrillo MA, Zhen A, Mu W, Rezek V, Martin H, Peterson CW, Kiem HP, Kitchen SG. Mol Ther. 2024 Feb 27:S1525-0016(24)00095-9. doi: 10.1016/j.ymthe.2024.02.026.

February 2024

Participant experiences in a combination HIV cure-related trial with extended analytical treatment interruption in San Francisco, United States
Dubé K, Ndukwe SO, Korolkova A, Dee L, Sugarman J, Sauceda JA. HIV Res Clin Pract. 2024 Jan 29;25(1):2312318. Epub 2024 Feb 13. PMID: 38348830.
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January 2024

Safety and virologic impact of haploidentical NK cells plus IL-2 or N-803 in HIV infection.
Miller JS, Rhein J, Davis ZB, Cooley S, McKenna D, Anderson J, Escandón K, Wieking G, Reichel J,
Thorkelson A, Jorstad S, Safrit JT, Soon-Shiong P, Beilman GJ, Chipman JG, Schacker TW. J Infect Dis. 2024 Jan 11:jiad578. doi: 10.1093/infdis/jiad578. Epub ahead of print. PMID: 38207119.
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