Child and Adolescent HIV Research

Child and Adolescent HIV
Photo: Kevin Tachman

TREAT Asia’s pediatric network includes 21 sites, 19 of which contribute to the TREAT Asia Pediatric HIV Observational Database (TApHOD). TApHOD is a regional pediatric HIV study set up by TREAT Asia in 2006 that includes data from more than 7,500 children and adolescents in Cambodia, India, Indonesia, Malaysia, Thailand, and Vietnam. Due to the success of national Prevention of Mother-to-Child HIV Transmission (PMTCT) programs and the resulting decline in pediatric HIV infections, since 2021 sites in Thailand and Malaysia stopped contributing new data to TApHOD.

TREAT Asia Pediatric Network
 Countries in the Asia-Pacific region with TApHOD sites (click on map to see specific sites)

Research priorities focus on investigating HIV clinical and treatment outcomes among children and adolescents living with HIV, including optimal antiretroviral regimen sequencing to reduce resistance and side effects, the longer-term consequences of failing first- or second-line treatment before adulthood, and HIV-associated co-infections and co-morbidities.  

Publications and analyses of TREAT Asia’s pediatric research network can be accessed at

TREAT Asia also studies the management of HIV in children and adolescents in the broader context of families and communities, and the complex psychosocial needs of young people navigating growing up with HIV, adhering to HIV treatment, reducing risk behaviors for transmitting HIV and transitioning into adult care. Additionally, TREAT Asia participates in the International AIDS Society’s (IAS) Collaborative Initiative for Pediatric HIV Education and Research (CIPHER), which aims to facilitate global collaboration to improve care for HIV-positive children and adolescents.


TREAT Asia Plans for Next Phase of Adolescent Research Program
An International Collaboration to Model the Adolescent HIV Epidemic in Thailand
TREAT Asia Holds Annual Network Meeting in Bangkok
Improving Care for Thai Youth Living with HIV
PERSPECTIVES: How can we improve mental health services for people living with HIV in the Asia-Pacific?
TREAT Asia and amfAR at the 22nd International AIDS Conference
PERSPECTIVES: Are integrase inhibitors the solution to HIV drug resistance in the Asia-Pacific region?
Evaluating Depression and Anxiety in Thai Adolescents with HIV
A Growing Threat: Study Highlights Risks of HPV Infection to HIV-Positive Young Women
TREAT Asia Begins New Initiative to Address Adolescent Mental Health
New NIH Grant for TREAT Asia and University of Cape Town Partnership on Adolescents Living With HIV
TREAT Asia Investigators Selected in Three Rounds of IAS CIPHER Grant Program
Supporting Children as They Transition Through Life
amfAR’s Dr. Annette Sohn Featured in South China Morning Post
Improving Reproductive Health in Young Thai Women
Surveying Gaps in Adolescent Care in the Asia-Pacific
Investigator Video: Improving Pediatric HIV Treatment in Asia
AIDS LIFE and TREAT Asia Team Up to Fight Pediatric HIV in Asia
Study Shows HIV-Positive Adolescents in Asia Are at Increased Risk of High-Risk HPV
amfAR’s Pediatric Cure Think Tank Features Thai Study
A New Study Addresses Data Gaps on Treatment Adherence Among Children and Adolescents
Community Profile: Worldwide Orphans Foundation Vietnam
Improving Reproductive Health Among HIV-Positive Adolescents
TREAT Asia Pediatric Researcher Receives an IAS CIPHER Grant
TREAT Asia Study on ARV Resistance in Children Reaches Its Goal
New Global Pediatric HIV Database to Investigate Critical Research Gaps