Cure – Clinical Trials and Cases

Cure — Clinical Trials and Cases

Before testing an agent or therapeutic approach in human subjects, researchers first need to show proof of concept or characterize how the agent behaves in vitro—in the laboratory. amfAR-funded researchers are testing a variety of approaches, such as boosting the immune system, gene therapy, and CAR T cells, which have proven highly successful in the treatment of certain types of cancer.

2024

Rejuvenating the Field of AIDS Research

A Person-Centered Cure

Enhancing Innate Immunity Against HIV

2023

New Case of Post-Treatment Control

New Case of Possible HIV Cure Reported

Solving the Puzzle of Post-Treatment Control

amfAR Cure Trial Shows Proof of Concept

Confirmed: Düsseldorf Patient Cured of HIV

How Do Some People Control HIV Without Antiretroviral Therapy?

2022

Blocking T-Cell Growth: Will It Shrink the Reservoir?  

Meet the London Patient: Adam Castillejo

The Issue of Tissue: Getting to the Source of the HIV Reservoir

How Many Have Been Cured?

New Case of HIV Cure Reported

Shock-and-Kill Trial Falls Short

Researchers Report Potential New Case of HIV Cure

2021

Stem Cell Transplants and the CCR5 Mutation

Researchers Report New Case of Spontaneous HIV Cure

Why Do Some Elite Controllers Stop Controlling HIV?

Reversing HIV Latency and Decreasing the Viral Reservoir: Clues from Cancer

Risks and Potential Benefits of Participating in Cure Research

2020

A Conversation with the San Francisco Patient

Research Update: Pioneering Clinical Trial Gets Underway

How Does the Immune System Recover After a Stem Cell Transplant?

Why Do HIV Reservoirs Persist After Stem Cell Transplants?

2019

amfAR Researchers Unable to Find HIV In London Transplant Patient