Approximately 40.9 million people worldwide are living with HIV.
Deaths from AIDS-related causes were estimated to be 570,000 in 2025.
51% of all people living with HIV (PLWH) are women and girls.
While 88% of PLWH were aware of their status in 2025, approximately 4.9 million did not know they were living with the virus.
The age group least likely to receive HIV treatment—children aged 0-14.
Half of all new infections occurred in sub-Saharan Africa.
Global development assistance from multiple countries, including for HIV programs, fell by 23% in 2025, the sharpest decline on record..
In 2025, someone died of HIV-related causes every minute.
New HIV infections
New HIV infections totaled 1.2 million.
Approximately 3,300 adults and children acquire HIV each day.
In 2025, 43% fewer people acquired HIV compared with 2010.
Members of key populations (men who have sex with men, people who inject drugs, sex workers, transgender women, and people who are incarcerated) and their sex partners accounted for over 49% of new infections.
AIDS-related deaths
Annual deaths from AIDS-related causes were estimated to be 570,000 in 2025, or one death every minute. Thanks to HIV testing and treatment access, there were 57% fewer AIDS-related deaths in 2025 than in 2010.
Eastern and southern Africa is the region with the most AIDS-related deaths: 240,000; Asia and the Pacific have the next highest number: 120,000. The Caribbean has the least: 4,700.
In 2025, 70,000 children died of AIDS-related causes.
In 2025, someone died of HIV-related causes every minute.
Access to treatment
32.1 million people (78% of all PLWH) were accessing antiretroviral therapy in 2025.
About half of the 8.8 million people in need of HIV treatment live in sub-Saharan Africa; about 25% live in Asia and the Pacific.
Along the continuum of care for all: 88% of PLWH knew their status in 2025; among them, 89% had accessed antiretroviral therapy; and 95% of PLWH on treatment had achieved viral suppression. By category:
Women (aged 15+ years): 91%-92%-95%
Men (aged 15+ years): 85%-87%-95%
Children: 64%-84%-85%
Access to Prevention Options/PrEP
The number of people receiving PrEP at least once in the reporting year declined by 38% from 2024 to 2025.
Data reported from countries to UNAIDS found that more than 60% of sex workers (52 countries), gay men and other men who have sex with men (49 countries), people who inject drugs (31 countries), and transgender people (25 countries) relied on nongovernmental organizations, including those led by people from key populations, for HIV prevention services.
HIV Among Key Populations
Key population programs, predominantly community-led groups and other nongovernmental organizations, are underfunded across all regions and now also threatened by funding cuts. People from key populations and their sex partners account for over 49% of all new HIV infections.
The risk of HIV acquisition compared with the adult population (aged 15-45 years) was estimated to be:
34 times higher among people who inject drugs
18 times higher among gay men and other men who have sex with men
17 times higher among transgender people
17 times higher among sex workers
HIV prevalence is 6 times higher among people in prisons and other closed settings.
HIV Among Adolescent Girls and Young Women/Adult Women
Gender-based violence impacts individuals beyond physical and traumatic effects—studies show that this type of violence increases HIV infection risk in countries with high HIV prevalence and decreases prevention uptake and use of services.
In 2025, 41% of all new infections occurred among women and girls.
Women are disproportionately affected by HIV in sub-Saharan Africa, accounting for 6 out of 10 acquisitions.
Adolescent girls and young women aged 15–24 remain at high risk for acquiring HIV, with 3,000 of these infections occurring in sub-Saharan Africa every week.
In 2025, 87% of pregnant and breastfeeding women living with HIV had access to antiretroviral treatment to prevent transmission of HIV to their children. However, there has been very little increase in this type of treatment coverage over the past decade.
HIV Among Children
The age group least likely to receive HIV treatment—children aged 0-14. Only 54% of this group (or 580,000 children) are on lifesaving medications.
Approximately 94,000 children (under 15) newly acquired HIV in 2025 globally, with the most impacted regions being eastern and southern Africa (46,000), western and central Africa (33,000), and Asia and the Pacific (8,200).
Children aged 0–14 years had the steepest decreases in numbers of new HIV infections, declining by 69% from 2010 to 2025.
Between 2000 and 2025, programs to prevent vertical (mother-to-child) transmission of HIV averted nearly 4.8 million new HIV infections in children.
In 2025, children accounted for 11% of all AIDS-related deaths, even though children are only 3% of all people living with HIV.
In total, roughly 1.3 million children were living with HIV in 2025.
In 2025, 64% of children living with HIV knew their status; 84% of those who knew their status were on ART; and 85% of those who knew their status had achieved viral suppression.
